Table 5.
Effect of value set characteristics on discriminatory performance in terms of F statistic and area under the receiver-operating characteristics curve
| F statistic | AUROC | |||||||
|---|---|---|---|---|---|---|---|---|
| Coefficient | t value | p value | 95% CI | Coefficient | t value | p value | 95% CI | |
| Healthy vs. disease | ||||||||
| Version 5La | – 37.3 | − 4.29 | 0.00 | − 56.1 to − 18.5 | − 0.015 | − 7.20 | 0.00 | − 0.020 to − 0.011 |
| Countryb | ||||||||
| China | 60.0 | 3.91 | 0.00 | 26.8 to 93.1 | 0.000 | 0.00 | 1.00 | − 0.007 to 0.007 |
| England/UK | − 27.3 | − 2.00 | 0.07 | − 56.7 to 2.1 | − 0.023 | − 6.42 | 0.00 | − 0.031 to − 0.015 |
| Japan | 73.4 | 3.57 | 0.00 | 29.0 to 117.8 | 0.013 | 3.75 | 0.00 | 0.005 to 0.020 |
| The Netherlands | − 50.2 | − 3.67 | 0.00 | − 79.8 to − 20.7 | − 0.037 | − 7.75 | 0.00 | − 0.047 to − 0.027 |
| South Korea | 53.3 | 5.54 | 0.00 | 32.5 to 74.1 | 0.018 | 6.66 | 0.00 | 0.012 to 0.024 |
| Spain | − 8.4 | − 0.47 | 0.65 | − 47.4 to 30.6 | − 0.015 | − 2.39 | 0.03 | − 0.028 to − 0.001 |
| Intercept | − 342.5 | − 3.67 | 0.00 | − 543.9 to − 141.0 | − 0.109 | − 4.43 | 0.00 | − 0.162 to − 0.056 |
| Modelled range | 50.4 | 1.25 | 0.23 | − 36.8 to 137.6 | 0.051 | 3.92 | 0.00 | 0.023 to 0.079 |
| N3 | − 57.5 | − 1.17 | 0.26 | − 163.9 to 49.0 | − 0.029 | − 1.68 | 0.12 | − 0.066 to 0.008 |
| Constant | 293.5 | 5.24 | 0.00 | 172.4 to 414.6 | 0.746 | 45.08 | 0.00 | 0.710 to 0.782 |
| Mild vs. moderate/severe | ||||||||
| Version 5La | 27.2 | 8.81 | 0.00 | 20.5 to 33.8 | 0.023 | 25.02 | 0.00 | 0.021 to 0.025 |
| Countryb | ||||||||
| China | 20.9 | 3.79 | 0.00 | 9.0 to 32.8 | − 0.004 | − 2.61 | 0.02 | − 0.008 to − 0.001 |
| England/UK | 0.0 | 0.00 | 1.00 | − 11.0 to 11.1 | − 0.008 | − 3.84 | 0.00 | − 0.012 to − 0.003 |
| Japan | 21.1 | 2.66 | 0.02 | 3.9 to 38.2 | 0.002 | 0.94 | 0.37 | − 0.003 to 0.007 |
| The Netherlands | − 5.0 | − 1.04 | 0.32 | − 15.5 to 5.4 | − 0.006 | − 3.62 | 0.00 | − 0.010 to − 0.003 |
| South Korea | 10.4 | 2.72 | 0.02 | 2.1 to 18.7 | 0.002 | 1.49 | 0.16 | − 0.001 to 0.006 |
| Spain | 8.5 | 1.33 | 0.21 | − 5.3 to 22.3 | − 0.008 | − 3.31 | 0.01 | − 0.013 to − 0.003 |
| Intercept | 60.5 | 1.70 | 0.11 | − 16.4 to 137.4 | − 0.057 | − 4.44 | 0.00 | − 0.085 to − 0.029 |
| Modelled range | − 11.1 | − 0.86 | 0.40 | − 39.0 to 16.7 | 0.015 | 4.80 | 0.00 | 0.008 to 0.022 |
| N3 | − 11.8 | − 0.67 | 0.52 | − 50.1 to 26.5 | − 0.017 | − 2.71 | 0.02 | − 0.031 to − 0.004 |
| Constant | 126.6 | 6.98 | 0.00 | 87.4 to 165.8 | 0.695 | 159.70 | 0.00 | 0.686 to 0.705 |
3L EQ-5D-3L, 5L EQ-5D-5L, AUROC area under the receiver-operating characteristics curve, CI confidence interval, N3 any level 3
aWith 3L as reference
bWith Canada as reference