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. 2018 May 9;9:447. doi: 10.3389/fphar.2018.00447

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Copyright © 2018 Liu, Yang, Mu and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Protective effect of EGCG against DEX-induced apoptosis in GIO. (A) Cell apoptosis was measured by immunohistochemistry (arrow indicates cytochrome C positive cells) and was statistically evaluated. (B) Flow cytometric analysis was used to measure apoptotic rate, and the level of apoptotic rate was statistically evaluated, as shown in the column. (C) Expression of apoptosis-related protein was measured by Western blot, and quantitated levels of protein were statistically evaluated, as shown in the column. The data were expressed as the mean ± SD. ^###P < 0.001, ^##P < 0.01, ^#P < 0.05 vs. control and ^∗∗P < 0.01, ^∗P < 0.05 vs. DEX.