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20(S)-Rg3 suppress AGEs-induced M1 macrophage activation and promote M2 polarization (A) Representative immunoblots of PPARγ, iNOS (M1 marker) and Arg-1 (M2 marker) in BMDMs and THP-1 cells. (B) Quantification of PPARγ, iNOS and Arg-1 expression relative to the β-actin level (n = 3 respectively for PPARγ, iNos and Arg-1 in BMDMs; n = 3, 3, 4 for PPARγ, iNos and Arg-1 in THP-1 cells). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.
