FIGURE 4.

20(S)-Rg3 reduce plaque burden in diabetic apoE–/– mice. (A) Representative images of en face Oil-Red O staining of aortas in four groups of mice. (B) Quantitative analysis of en face aorta lesions expressed as percentage lesion area relative to total aorta area (n = 5, respectively). (C) Representative images of cross-sectional aortic root lesions by H&E staining. Scale bar: 200 μm. (D) Quantitative analysis of cross-sectional plaque area in aortic roots (n = 5, respectively). Data are mean ± SEM. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001.