FIGURE 5.

20(S)-Rg3 stabilizes atherosclerotic plaque in diabetic apoE–/– mice. (A) Representative staining of lipids, macrophages, smooth muscle cells (SMCs), and collagen in the aortic roots in four groups of mice. (B) Quantification of the plaque composition in four groups of mice, expressed as the percentage of the positive staining area to the total plaque area. (C) Vulnerability index in four groups of mice (n = 5, respectively). Scale bar: 50 μm. Data are mean ± SEM. ^∗p < 0.05, ^∗∗p < 0.01, ^∗∗∗p < 0.001.