TABLE 5.

GO categories of common mH2A1.2 target (within 5 kb on either side of the TSS) nonexpressed genes^a in human ESCs and human fibroblasts

Biological function(s) (GO category)	Log10 P value
Chromatin silencing at rDNA	54.23
Telomere organization, nuclear chromosome, telomeric region	50.66
Negative regulation of gene expression, epigenetic	49.41
DNA replication-dependent nucleosome assembly	47.74
Positive regulation of gene expression, epigenetic	46.35
Nucleosome core, nucleosome, nucleosome assembly	44.64
Protein heterotetramerization, protein heterodimerization activity	43.85
Citrullination	43.51
Histone fold, histone binding	40.51
Gene silencing by RNA	38.89
Histone H4, conserved site	31.06
TATA box binding protein associated factor (TAF)	29.46
Telomere capping	26.27
DNA replication-independent nucleosome assembly	25.31
DNA-templated transcription, initiation	22.96
Histone H3	22.30
Beta-catenin-TCF complex assembly	21.80
CENP-A-containing nucleosome assembly	21.80
Double-strand break repair via nonhomologous end joining	19.36
Extracellular region	18.96
Regulation of gene silencing	17.51
Methylation	16.52
Chromosomal rearrangement	11.43

^aCommon nonexpressed genes in hESCs and hFBSs occupied by mH2A1.2.