FIG 1 .

L. monocytogenes enhanced cell-to-cell spread in RECON-deficient hepatocytes. (A) Images of L. monocytogenes plaques (white) spreading through a monolayer of TIB73 cells (black area) for 72 h in a 6-well plate. (B) Quantification of plaque areas shown in panel A. (C) Images of L. monocytogenes cells (green) spreading through TIB73 cells (black area) for 8 h. The dotted line indicates the edge of the focus area. Scale bar, 50 µm. (D) Quantification of focus areas shown in panel C. Median values are indicated by a bar. All data points are shown and are plotted as the percentage of spread in WT TIB73 cells. Data are representative of more than 4 independent experiments. ***, P ≤ 0.0001.