Skip to main content
. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Mol Cancer Res. 2017 Jun 8;15(10):1366–1375. doi: 10.1158/1541-7786.MCR-17-0143

Figure 3. Depletion of ERRα compromises the growth of human melanomas.

Figure 3

A. Growth curve of various PGC1α -positive melanoma cell lines with ERRα depletion. B. End-point tumor weight of PGC1α-positive melanoma cells with ERRα depletion after inoculated into nude mice. Data were presented as mean with SD. C. Immunoblotting of PGC1α-negative melanoma cells upon ERRα depletion by CRISPR. D. Growth curve of PGC1α -negative melanoma cell lines with ERRα depletion. E. End-point tumor weight of PGC1α-melanoma cell line A375 with ERRα depletion in nude mice. *P < 0.05, **P < 0.01, ***P < 0.001 and n.s. (not significant) as determined by t-test if not otherwise indicated.