Table 2.
The number of significantly expressed genes (multiple-testing adjusted p-value < 0.05, fold change > 2) between each non-UIP subtype and UIP samples (N = 212). The number of differentially expressed genes overlapping with those between UIP and non-UIP samples was summarized in the third columns
| Up-regulated genes | Down-regulated genes | Total number of differentially expressed genes | # genes overlapping with those from all non-UIP samples | |
|---|---|---|---|---|
| All non-UIP (N = 147) | 55 | 96 | 151 | 151 (100%) |
| Bronchiolitis (N = 10) | 41 | 34 | 75 | 6 (8%) |
| Hypersensitivity pneumonitis (HP) (N = 13) |
32 | 53 | 85 | 14 (16%) |
| Nonspecific interstitial pneumonia (NSIP) (N = 12) |
37 | 49 | 86 | 13 (15%) |
| Organizing pneumonia (OP) (N = 23) |
1 | 15 | 16 | 31 (52%) |
| Respiratory bronchiolitis (RB) (N = 16) |
549 | 152 | 701 | 64 (9%) |
| Sarcoidosis (N = 11) | 448 | 726 | 1174 | 93 (8%) |