Figure 3.

Sarcomere length dynamics at physiologic baseline and in acidosis. (A–C) Shown are representative traces of sarcomere length dynamics, with normalized baseline sarcomere lengths shown as a percent change in length from baseline (solid trace = pH 7.4, dotted track = pH 6.2). (D) pH 6.2 sarcomere length dynamics showing the fractional shortening summary are given. (E) Shown is the change in fractional shortening from pH 6.2 to pH 7.4. n = 37–55 myocytes from four independent experiments for each group. Mean ± SE are presented. ^∗p < 0.05 from a one-way analysis of variance.