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. 2018 Apr 10;114(7):1646–1656. doi: 10.1016/j.bpj.2018.02.015

Figure 5.

Figure 5

Atomistic ribbon structures of TnI helix 4 (blue) interactions with cTnC (red) (A) A representative 40 ns frame of ssTnI cTnI HSD showing R139 of ssTnI interaction with cTnC E15 is given. The inset shows distances between E15 and R139. (B) A representative 40 ns frame of cTnI A164P HSD showing R171 of cTnI interaction with cTnC E15 is given. The inset shows distances between E15 and R171. (C) Shown is the calculated distance measurement from TnI R139/171 for ssTnI and cTnI A164P, respectively, to cTnC E15 during the 40 ns simulation. (D) The mean distance between ssTnI R139 or cTnI A164P R171 to cTnC E15 over the entire stable 40 ns of each simulation is given. Error bars are ±SE, and ∗p < 0.05 from a one-way analysis of variance. To see this figure in color, go online.