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Point Estimates of Sensitivity and Specificity of the SMS in the Three Tested Cohorts
| Study (no. in cohort) | Set at Sensitivity of 95% | Set at Youden Optima | ||
|---|---|---|---|---|
| Sensitivity | Specificity | Sensitivity | Specificity | |
| Smith et al [27] (94) | 0.959 | 0.356 | 0.837 | 0.933 |
| Wynn et al [23] (84) | 0.946 | 0.717 | 0.865 | 0.870 |
| Cernada et al [29] (36) | 0.941 | 0.737 | 1 | 0.737 |
| Overall mean | 0.949 | 0.603 | 0.901 | 0.847 |
Two methods for choosing an optimal point were used, a minimum sensitivity (95%) and the Youden joint maximization.
