Table 1. Gelation Time (GT), Gelation Fraction (GF), and Swelling Kinetics (Equilibrium Water Content, EWC) of Hydrogels at 10 w/v% in PBS Solution (1:1 Molar Ratio of Alkyne to Thiol End Groups)a.
| GTb (s) | GF (%) | EWC (%) | Mesh Sizec (nm) | |
|---|---|---|---|---|
| 31A21S | 210 ± 7 | 74 ± 2.6 | 95 ± 0.9 | 5.8 ± 0.49 |
| 31A22S | 290 ± 10 | 80 ± 1.9 | 94 ± 0.8 | 6.4 ± 0.16 |
| 31A23S | 438 ± 5 | 78 ± 4.9 | 95 ± 0.1 | 5.9 ± 0.03 |
| 31A31S | 26 ± 3 | 78 ± 1.2 | 90 ± 0.2 | 4.2 ± 0.07 |
| 31A42S | 25 ± 9 | 75 ± 1.3 | 90 ± 0.5 | 4.7 ± 0.14 |
| 42A31S | 15 ± 5 | 92 ± 0.7 | 87 ± 1.7 | 4.4 ± 0.47 |
| 42A42s | 11 ± 2 | 89 ± 1.8 | 86 ± 0.9 | 4.4 ± 0.24 |
| 31A2P3S | 10 min | 79 ± 1.3 | 58 ± 9.8 | 1.2 ± 0.48 |
| 31A23S-6040 | 8–10 min | 84 ± 1.2 | 86 ± 0.2 | 3.7 ± 0.04 |
a
The hydrogel naming (XZAYZS) denotes its structure, where X = number of arms of the alkyne precursor, Y = number of arms of the thiol precursor, and Z = molecular weight of the PEG precursor.
b
Measured via the vial tilt methods.
c
Calculated from the Flory–Rehner equation (see SI).