Table 2.

Apixaban concentration, treatment, and clinical course

	aFXa (μg/L)	Time from last apixaban dose to surgery	aPCC dose	Excessive perioperative or postoperative bleeding	Thromboembolic complications
Patient 1	69	24 hours	25 IU/kg	No	No
Patient 2	152	10 hours	28 IU/kg	No	No
Patient 3	98	9 hours	29 IU/kg	Yes	No

aFXa anti-factor Xa activity, aPCC activated prothrombin complex concentrate