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. 2018 May 16;7:48. doi: 10.1186/s40249-018-0433-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Histopathological examination of liver and spleen tissues from each group. The isolated spleen and liver samples were fixed in 4% formaldehyde, embedded in paraffin and sectioned. The sections (5 μm) were stained with H&E and evaluated under a microscope at 400 × magnification. The Con group shows normal structures and no infiltrated neoplasm cells in the liver and spleen. The P. yoelli (Py) group shows normal structures and no infiltrated neoplasm cells but shows deposition of malaria pigments in the liver and spleen. The WEHI-3 group shows abundant infiltrated neoplasm cells in the liver and spleen. The WEHI-3 + Py group shows markedly reduced neoplasm cell infiltration in the liver and spleen