Table 2: The ABCDE of diabetes fatigue syndromes.

	Nutritional/Physiologic	Psychosocial	Biomedical
A	Ageing	Apnoea (obstructive sleep apnoea): poor sleep hygiene, sleep deprivation	Anaemia: iron deficiency, renal impairment, drug induced
B	Vitamin B1, B6, B12 deficiency	Behavioural issues: diabetes distress, depression	Bulimia/anorexia nervosa
C	Calorie restriction/inadequacy	Conditioning, poor physical	Comorbid conditions: renal, hepatic, gastrointestinal disease
D	Vitamin D deficiency	Drug-induced: glucose-lowering, non-metabolic drugs; complementary and alternative medicine/substance abuse	Diabetes complications: nephropathy, heart failure, infections/infestations
E	Dyselectrolytemia	Exercise, lack of	Endocrine dysfunction: thyroid, adrenal, gonad