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Potential modulation of SP-D function
| Altered patterns of oligomerization |
| Liberation of trimeric subunits secondary to proteolytic degradation |
| Self-aggregation |
| Modifications of the CRD |
| Proteolytic degradation |
| Oxidative modification |
| Local pH and calcium concentration |
| Competing ligands |
| LPS |
| Microorganisms |
| Host lectins with overlapping specificity |
| Mannose receptor |
| Other collectins (SP-A, mannose-binding lectin) |
| Non C-type lectins (such as ficolins) |
