Table 1.

Effect and possible application of the novel drugs.

Drug	Effect	Possible application
ROCK inhibitor	Corneal endothelial cell regeneration	Topical eye drops for recovery of corneal clarity in corneal endothelial dysfunction
	Promotion of corneal endothelial cell adhesion	Adjuvant therapy for the corneal endothelial cell injection
Blood-derived products	Promotion of healing of ocular surface epithelium	Recovery of persistent epithelial defect or neurotrophic keratitis
		Promoting ocular surface regeneration and prevention of corneal haze after ocular chemical injury or keratorefractive surgery
Growth factors	Facilitation of corneal epithelial healing and nerve regeneration	Treatment of persistent epithelial defect or neurotrophic keratitis
		Topical eye drops for diabetic keratopathy
		Recovery of cornea epithelium and nerve after keratorefractive surgery
RGTA∗	Promotion of corneal regeneration and attenuation of ocular surface inflammation	Treatment of persistent epithelial defect or neurotrophic keratitis
		Recovery of corneal epithelium after corneal cross-linking
		Corneal recovery after keratorefractive surgery

^∗RGTA: regenerating agent eye drops.