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β-Arrestin deficiencies lead to decreased cholesterol levels. Free and total cholesterol levels of liver tissues of arrb1/2-knockout (KO) mice (a, b) and ARRB1/2-knockdown (KD) HepG2 cells (c, d). Cholesterol levels were standardized by protein concentration and were expressed as mmol cholesterol per gram of protein. The differences between groups were compared by using nonparametric tests. ∗p < 0.05 versus control group. Error bars are calculated as a standard error (SEM).
