Chronic treatment with paclitaxel does not reduce basal PKC α, βI or βII, immunoreactivity in cultured sensory neurons. (A, C, E) Representative western blot images showing immunoreactivity for PKC α, βI and βII in whole cell lysates in neurons treated with vehicle and paclitaxel (300 nM, 3 days). (B, D, F) Densitometry analysis showing no significant differences in PKC immunoreactivity normalized to actin in paclitaxel-treated (300 nM, 3 days) neurons compared to vehicle-treated neurons using a t-test (N = 3–4, a.u. ± SEM). Veh - Vehicle; Pac -Paclitaxel.