Table 1.
Clinicopathological characteristics and expression of circ_0066444
Variables | Cases | Normal expression | Overexpression | χ2 | P-value |
---|---|---|---|---|---|
Age (year) | 106 | 2.964 | 0.087 | ||
≥60 | 86 | 12 | 74 | ||
<60 | 20 | 6 | 14 | ||
Gender | 106 | 2.681 | 0.083 | ||
Female | 48 | 5 | 43 | ||
Male | 58 | 13 | 45 | ||
Diameter | 106 | 0.159 | 0.454 | ||
≥3 (cm) | 86 | 14 | 72 | ||
<3 (cm) | 20 | 4 | 16 | ||
Differentiation | 0.382 | 0.465 | |||
Low/middle | 93 | 17 | 79 | ||
Well | 10 | 1 | 9 | ||
Lymphatic metastasis | 106 | 4.979 | 0.023* | ||
Yes | 71 | 8 | 63 | ||
No | 35 | 10 | 25 | ||
TNM stage | 106 | 4.508 | 0.262 | ||
I+IIA | 36 | 10 | 26 | ||
IIB–IV | 70 | 8 | 62 | ||
CEA | 106 | 1.247 | 0.207 | ||
High | 29 | 3 | 26 | ||
Normal | 77 | 15 | 62 | ||
CA199 | 106 | 0.442 | 0.375 | ||
High | 24 | 3 | 21 | ||
Normal | 82 | 15 | 67 | ||
CA50 | 106 | 1.107 | 0.265 | ||
High | 14 | 1 | 13 | ||
Normal | 92 | 17 | 75 | ||
CA242 | 106 | 0.135 | 0.501 | ||
High | 21 | 3 | 18 | ||
Normal | 85 | 15 | 70 |
Note:
Mean P<0.05.
Abbreviation: TNM, tumor–node–metastasis.