Table 2.
PEEP | SB | Time after the Start of the Protocol |
||
---|---|---|---|---|
1 h | 8 h | 16 h | ||
PaO2/FiO2, mm Hg | ||||
High | + | 342 ± 105 | 409 ± 46* | 412 ± 53* |
Low | + | 222 ± 118 | 221 ± 97 | 246 ± 100 |
| ||||
Plateau airway pressure, cm H2O | ||||
High | + | 29 ± 4.2 | 26.2 ± 2.5 | 27 ± 2.2 |
Low | + | 25.4 ± 2.7 | 25.7 ± 4.6 | 25 ± 3.5 |
| ||||
Mean airway pressure, cm H2O | ||||
High | + | 21.1 ± 2.7* | 20 ± 2.1* | 20.3 ± 1.6* |
Low | + | 14.8 ± 2.5 | 14.7 ± 2.5 | 14 ± 1.9 |
| ||||
PEEP, cm H2O | ||||
High | + | 15 ± 2* | 15 ± 2* | 15 ± 2* |
Low | + | 8 ± 3 | 7 ± 2 | 7 ± 2 |
| ||||
Peak transpulmonary pressure, cm H2O | ||||
High | + | 23.3 ± 4.5 | 21.0 ± 2.6 | 21.4 ± 2.3 |
Low | + | 26.4 ± 2.7 | 26.0 ± 4.1 | 26.2 ± 4.8 |
| ||||
Peak ∆ transpulmonary pressure, cm H2O | ||||
High | + | 17.8 ± 2.0* | 15.6 ± 2.7* | 15.9 ± 3.4* |
Low | + | 26.9 ± 2.7 | 26.0 ± 4.1 | 26.2 ± 4.8 |
| ||||
Dynamic compliance of respiratory system, ml/cm H2O | ||||
High | + | 11.2 ± 2.0* | 12.2 ± 2.7* | 13.0 ± 2.9* |
Low | + | 8.5 ± 1.6 | 8.9 ± 4.0 | 9.2 ± 3.5 |
| ||||
Vt, ml/kg | ||||
High | + | 6.1 ± 0.6 | 5.7 ± 0.6 | 6.2 ± 0.8 |
Low | + | 6.4 ± 0.7 | 6.0 ± 0.7 | 6.3 ± 1.0 |
| ||||
Respiratory rate, breaths/min | ||||
High | + | 36 ± 5* | 36 ± 6* | 36 ± 8* |
Low | + | 58 ± 4 | 54 ± 9 | 54 ± 11 |
| ||||
PaCO2, mm Hg | ||||
High | + | 67 ± 15 | 61 ± 17 | 60 ± 11 |
Low | + | 55 ± 9 | 61 ± 12 | 60 ± 16 |
| ||||
pH | ||||
High | + | 7.3 ± 0.1 | 7.3 ± 0.1 | 7.3 ± 0.1 |
Low | + | 7.3 ± 0.1 | 7.3 ± 0.1 | 7.3 ± 0.1 |
For definition of abbreviations, see Table 1.
Data presented are mean ± SD.
P < 0.05 compared with low PEEP + SB.