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. 2018 Apr 24;9(31):21715–21730. doi: 10.18632/oncotarget.24922

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Copyright: © 2018 Khoury et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Daily urinary sodium excretion (UNaV) in rats with aortocaval fistula (ACF) and in sham controls. Notice two distinct patterns of sodium excretion in rats with ACF, compensated and decompensated rats. The lines representing compensated and decompensated CHF were significantly different (P < 0.01, by 2-way ANOVA). Similarly, the lines representing both CHF rats are significantly different from sham- operated animals (P < 0.01). (B) Glomerular filtration rate (GFR), and (C) Renal plasma flow (RPF) in rats with compensated and decompensated CHF and their sham controls. ^*P < 0.05 vs. sham-operated rats; ^#P < 0.05 vs. compensated rats with ACF. Values are means ± SEM.