Table 3. Treatment toxicities.
Monthly Carboplatin N (%) | Weekly Carboplatin N (%) | |
---|---|---|
Total of toxicities | 88 | 40 |
Any grade toxicity leading to modification of treatment | ||
Dose reduction | 53 (60%) | 7 (18%) |
With modification of monthly Carboplatin in weekly Carboplatin | 11 (13%) | |
Cessation of treatment | 16 (18%) | 9 (23%) |
Anemia | 45 (51%) | 10 (25%) |
≥grade 3) | 23 (26%) | 1 (3% |
Thrombopenia | 26 (30%) | 8 (20%) |
≥grade 3 | 7 (8%) | 0 (0%) |
Neutropenia | 46 (52%) | 20 (50%) |
≥grade 3 | 35 (40%) | 11 (28%) |
Febrile neutropenia | 12 (14%) | 5 (13%) |
Leading death | 1 (1%) | 1 (3%) |
Infection without aplasia | 39 (44%) | 14 (35%) |
Digestive toxicity | 17 (19%) | 5 (13%) |
≥grade 3 | 1 (1%) | 0 (0%) |
Neuropathy | 10 (11%) | 3 (8%) |
≥grade 3 | 2 (2%) | 1 (3%) |