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. 2018 Apr 24;9(31):22038–22046. doi: 10.18632/oncotarget.25157

Table 3. Treatment toxicities.

Monthly Carboplatin N (%) Weekly Carboplatin N (%)
Total of toxicities 88 40
Any grade toxicity leading to modification of treatment
 Dose reduction 53 (60%) 7 (18%)
 With modification of monthly Carboplatin in weekly Carboplatin 11 (13%)
 Cessation of treatment 16 (18%) 9 (23%)
Anemia 45 (51%) 10 (25%)
 ≥grade 3) 23 (26%) 1 (3%
Thrombopenia 26 (30%) 8 (20%)
 ≥grade 3 7 (8%) 0 (0%)
Neutropenia 46 (52%) 20 (50%)
 ≥grade 3 35 (40%) 11 (28%)
Febrile neutropenia 12 (14%) 5 (13%)
 Leading death 1 (1%) 1 (3%)
Infection without aplasia 39 (44%) 14 (35%)
Digestive toxicity 17 (19%) 5 (13%)
 ≥grade 3 1 (1%) 0 (0%)
Neuropathy 10 (11%) 3 (8%)
 ≥grade 3 2 (2%) 1 (3%)