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. 2018 Apr 24;9(31):21770–21782. doi: 10.18632/oncotarget.24985

Figure 1. Histological changes in the rat testes.

Figure 1

Transverse sections of testis tissue were stained with hematoxylin and eosin (HE). Scale bar = 1000 μm. (A-D) Magnification: ×100; (E-H) Magnification: ×200. Control group with normal histology of seminiferous tubules and interstitium (A&E). Oligoasthenospermia model group with loss of spermatogenic cells, degeneration of interstitial cells, and vacuolization in the cytoplasm of Sertoli cells (B&F). Low-dose QLPs group with increased numbers of spermatogenic cells, hyperplasia of interstitial cells, and decreased number of vacuoles in Sertoli cells (C&G). High-dose QLPs group with further enhancement of tissue recovery as compared to the low-dose QLPs group (D&H).