Figure 2.

Curcuminoids prevent iron-induced lipid peroxidation. Confluent T51B cells were treated for 2 h ± 200 μM iron and ±10 μM 8-hydroxyquinoline (8HQ) as indicated. Curcuminoids were added with iron/8HQ as either purified curcuminoids (curc at 2, 10, or 50 μM) or a standardized turmeric extract (turm at 2, 10, or 50 μM). Cell lysates were analyzed by TBARS assay and results expressed in MDA equivalents. Means ± SE from 4 replicate experiments are presented. (***P < 0.001 vs. iron + 8HQ reference (ref.); **P < 0.01; *P < 0.05.)