Table 2.
Baseline Echocardiographic, Laboratory, and Hemodynamic Characteristics
| Total n = 74 |
Event-Free n = 53 |
Adverse Event n = 21 |
P-value | |
|---|---|---|---|---|
| Admission Echo | ||||
| LV Ejection Fraction (%) | 14.6 (6.0) | 14.7 (6.3) | 14.5 (5.6) | 0.93 |
| LVEDd (cm) | 6.6 (1.4) | 6.8 (1.3) | 6.1 (1.3) | 0.03 |
| MR, ≥ moderate (n,%) | 33 (45%) | 23 (43%) | 10 (48%) | 0.74 |
| TR, ≥ moderate (n,%) | 28 (38%) | 23 (43%) | 5 (24%) | 0.18 |
| RV dilation, ≥ moderate (n,%) | 9 (12%) | 7 (13%) | 2 (9%) | 1.00 |
| RV dysfunction, ≥ moderate (n,%) | 34 (46%) | 21 (40%) | 13 (62%) | 0.12 |
| Laboratory Data | ||||
| Troponin I (ng/mL) | 1.2 (2.9) | 0.9 (2.6) | 1.9 (3.4) | 0.18 |
| Creatinine (mg/dL) | 2.1 (1.3) | 2.1 (1.3) | 2.2 (1.2) | 0.77 |
| Lactate (mmol/L) | 3.2 (3.8) | 2.8 (3.3) | 4.2 (4.9) | 0.16 |
| PA Oxygen Saturation (%) | 51.0 (14.8) | 51.2 (14.6) | 50.4 (15.5) | 0.83 |
| Pro-BNP (pg/mL) | 9849 (7332) | 8847 (6793) | 12253 (8238) | 0.13 |
| VS/Hemodynamic Data | ||||
| Systemic Oxygen Saturation (%) | 96.4 (3.9) | 96.7 (3.2) | 95.9 (5.2) | 0.42 |
| Intubated (n,%) | 7 (10%) | 2 (4%) | 5 (24%) | 0.02 |
| On Inotrope (n,%) | 65 (88%) | 48 (91%) | 17 (81%) | 0.26 |
| Heart Rate (min−1) | 102 (20) | 99 (21) | 110 (17) | 0.04 |
| Systolic BP (mm Hg) | 93 (13) | 93 (13) | 92 (12) | 0.78 |
| Diastolic BP (mm Hg) | 60 (10) | 61 (10) | 59 (10) | 0.39 |
| Mean Arterial Pressure (mm Hg) | 72 (10) | 72 (10) | 71 (9) | 0.79 |
| Right Atrial Pressure (mm Hg) | 18 (7) | 18 (7) | 18 (7) | 0.93 |
| PA Systolic Pressure (mm Hg) | 53 (13) | 53 (11) | 51 (16) | 0.70 |
| Mean PA Pressure (mm Hg) | 38 (10) | 38 (8) | 38 (12) | 0.82 |
| PA Diastolic Pressure (mm Hg) | 29 (8) | 29 (8) | 29 (8) | 0.75 |
| PCWP (mm Hg) | 28 (8) | 29 (7) | 27 (9) | 0.34 |
| Cardiac Index (L/min/m2) | 1.74 (0.59) | 1.86 (0.62) | 1.44 (0.41) | 0.007 |
| SVR (dyn·s·cm−5) | 1342 (596) | 1246 (555) | 1578 (641) | 0.03 |
| PVR (Wood units) | 3.2 (2.5) | 2.8 (1.8) | 4.2 (3.6) | 0.14 |
| Stroke Volume Index (ml/m2/beat) | 17.8 (7.8) | 19.5 (8.1) | 13.5 (4.7) | 0.003 |
| LV Stroke Work Index (g/m2/beat) | 10.6 (5.8) | 11.6 (6.4) | 8.0 (3.2) | 0.016 |
| RV Stroke Work Index (g/m2/beat) | 4.8 (3.1) | 5.3 (3.2) | 3.6 (2.5) | 0.05 |
| LV Cardiac Power Index (W/m2) | 0.28 (0.10) | 0.29 (0.11) | 0.22 (0.07) | 0.009 |
| RV Cardiac Power Index (W/m2) | 0.14 (0.05) | 0.16 (0.05) | 0.12 (0.05) | 0.007 |
For continuous variables, Student’s T-test was used to compare, or Mann--Whitney Rank Sum Test where appropriate. For categorical variables, Chi square test was used to compare, or Fisher’s exact test where appropriate. LVEDd, LV End-Diastolic dimension; MR, mitral regurgitation; TR, tricuspid regurgitation; PA, pulmonary artery; Pro-BNP, pro-brain natriuretic peptide; BP, blood pressure; PCWP, pulmonary capillary wedge pressure; SVR, systemic vascular resistance; PVR, pulmonary vascular resistance.