Table 4. Five-year overall survival rates of patients with ESCC according to various clinicopathological parameters.
| Variable | Univariate | Multivariate | ||||
|---|---|---|---|---|---|---|
| n=61 | 5-year OS rate (%) | p value * | HR | 95% CI | p value ** | |
| Gender | ||||||
| Male | 52 | 64.6 | 0.538 | |||
| Female | 9 | 75 | ||||
| Age | ||||||
| <65 years | 26 | 76 | 0.182 | |||
| ≥65 years | 35 | 58.8 | ||||
| Tumor length | ||||||
| <50 cm | 41 | 67.1 | 0.591 | |||
| ≥50 cm | 20 | 64.3 | ||||
| Histological type | ||||||
| Well/Moderately | 44 | 71.6 | 0.192 | |||
| Poorly | 17 | 52.9 | ||||
| Lymphatic invasion | ||||||
| Positive | 32 | 57.9 | 0.099 | 2.51 | 0.921-7.374 | 0.0724 |
| Negative | 29 | 74.8 | ||||
| Venous invasion | ||||||
| Positive | 32 | 52.5 | 0.045 | 3.203 | 1.206-9.175 | 0.0192 |
| Negative | 29 | 77.6 | ||||
| Pathological depth of the tumor | ||||||
| pT1 | 27 | 77.4 | 0.054 | 2.694 | 0.964-8.299 | 0.0589 |
| pT2-3 | 34 | 56.6 | ||||
| Pathological lymph node metastasis | ||||||
| pN0 | 27 | 73.5 | 0.207 | |||
| pN1-3 | 34 | 59.7 | ||||
| IHC score | ||||||
| ≤ 0.1 or ≥ 0.9 | 29 | 44.8 | 0.001 | 10.31 | 3.542-35.70 | <0.0001 |
| Others | 32 | 84.2 | ||||
OS: overall survival; HR: hazard ratio; CI: confidence interval.
* Log-rank test. ** Cox’s proportional hazards model.