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. 2018 May 1;9(33):23237–23252. doi: 10.18632/oncotarget.25296

Table 4. Five-year overall survival rates of patients with ESCC according to various clinicopathological parameters.

Variable Univariate Multivariate
n=61 5-year OS rate (%) p value * HR 95% CI p value **
Gender
 Male 52 64.6 0.538
 Female 9 75
Age
 <65 years 26 76 0.182
 ≥65 years 35 58.8
Tumor length
 <50 cm 41 67.1 0.591
 ≥50 cm 20 64.3
Histological type
 Well/Moderately 44 71.6 0.192
 Poorly 17 52.9
Lymphatic invasion
 Positive 32 57.9 0.099 2.51 0.921-7.374 0.0724
 Negative 29 74.8
Venous invasion
 Positive 32 52.5 0.045 3.203 1.206-9.175 0.0192
 Negative 29 77.6
Pathological depth of the tumor
 pT1 27 77.4 0.054 2.694 0.964-8.299 0.0589
 pT2-3 34 56.6
Pathological lymph node metastasis
 pN0 27 73.5 0.207
 pN1-3 34 59.7
IHC score
 ≤ 0.1 or ≥ 0.9 29 44.8 0.001 10.31 3.542-35.70 <0.0001
 Others 32 84.2

OS: overall survival; HR: hazard ratio; CI: confidence interval.

* Log-rank test. ** Cox’s proportional hazards model.