Table 4. Immune cell landscape compared with gene expression.
Tumor purity | B cell | CD8+ T cell | CD4+ T cell | Macrophage | Neutrophil | Dendritic cell | |
---|---|---|---|---|---|---|---|
r | r | r | r | r | r | r | |
IL-34 | -- | ++ | − | + | + | ||
CSF-1 | -- | + | + | ++ | ++ | +++ | ++ |
CSF-1R | -- | ++ | ++ | +++ | +++ | +++ | +++ |
PTPRZ1 | − | − | |||||
SDC1 | − | + | + |
Categorized Pearson’s product-moment correlation of immune cell landscape of breast cancer compared with TCGA gene expression of IL-34, CSF-1, CSF-1R, PTPRZ1, and SDC1 (syndecan-1) (TIMER).
r, categorized Pearson’s correlation coefficient;
(---), −1.0 to −0.5, strong negative association; (--), −0.5 to −0.3, weak negative association; (−), −0.3 to 0.1, little association.
(+), +0.1 to 0.3, little association; (++) +0.3 to +0.5, weak positive association; (+++), +0.5 to +1.0, strong positive association.