Table 5. Macrophage infiltration scores and stromal score compared with gene expression.

	Monocytes	M0	M1	M2	Stromal sc
	r	r	r	r	r
IL-34			++	--	+
CSF-1	+		+		++
CSF-1R			+		+++
PTPRZ1			+	−
SDC1		+			++

Categorized Pearson’s product-moment correlation correlation between IL-34, CSF-1, CSF-1R, PTPRZ1 and SDC1 (syndecan-1) mRNA expression and M0, M1, M2 and monocyte infiltration scores (obtained from TCIA database) in tumor samples from the TCGA BRCA dataset. M0, M0 macrophages; M1, M1 macrophages; M2, M2 macrophages; Stromal sc, Stromal score; r, categorized Pearson’s correlation coefficient;

(---), −1.0 to −0.5, strong negative association; (--), −0.5 to −0.3, weak negative association; (−), −0.3 to 0.1, little association.

(+), +0.1 to 0.3, little association; (++) +0.3 to +0.5, weak positive association; (+++), +0.5 to +1.0, strong positive association.