Table 5. Correlation of molecular aberration.
Variable | Carvajal et al. [28] | Guo et al. [8] | Hodi et al. [32] | Lee et al. [33] | Yun et al. [34] | Present Study |
---|---|---|---|---|---|---|
KIT mutation, n | 24 | 40 | 13 | 27 | 7 | 7 |
Exon 11 | 9 (37.5%) | 17 (42.5%) | 9 (69.3%) | 17 (62.9%) | 5 | 3/7 (42.8) |
Exon 13 | 6 (25%) | 9 (22.5%) | 3 (23.1%) | 6 (22.2%) | 1 | 1/7 (14.3) |
Exon 9 | NA | NA | NA | NA | NA | 3/7 (42.8) |
Exon 17 | NA | NA | NA | NA | 1 | NA |
Specific mutation type | ||||||
Exon 11 L576P | 7 (77.8%) | NA | 3 (33.3%) | 5 (29.4%) | 2 (40%) | 1 (33.3%) |
Exon 13 K642E | 4 (66.6%) | NA | 3 (100%) | 1 (16.7%) | NA | NA |
Other Mutations | No | NA | Exon 11 insetion PYD577-582 Exon 17 D820Y Exon 11 V560D |
Exon 17 I817L Exon 11 deletion Exon 11 V559A |
NA | Exon 11 V551 Exon 13 L657F Exon 9 L455M, S480F, G499S |
NA, not available.