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. 2017 Aug 18;9(1):121–132. doi: 10.1080/21505594.2017.1358349

Table 3.

Antigenicity evaluation of wild-type and mutated epitopes. The effect of mutations on the antigenicity (threshold level = 0.4) of predicted B cells epitopes. Bold letters (one-letter amino acid code) represent mutations within the predicted epitopes.

Region/Genotype Epitopes name Position Wild-type B cell epitopes Antigenicity Mutated B cell epitopes Antigenicity
  B1 F179S FRHGMTRLY 0.1 F/SRHGMTRLY 0.1
ORF1/GT1 B2 T735I TPAAPLPPP 0.1 T/IPAAPLPPP 0.1
  B3 L1110F TTSRVLRSL 0.1 TTSRVL/FRSL 0.01
  B4 V1120I WGEPAVGQK 0.8 WGEPAV/IGQK 1
  B5 F1439Y FYGDAFDDT 0.2 FYGDAF/YDDT 0.2
  B6 G1634K SDFLRKLTN 0.1 SDFLRG/KLTN −0.1
ORF2/GT1 B7 L477T SLTAAEYDQ 1.1 SLL/TAAEYDQ 1.0
  B8 L613T LLDYPARAH 0.4 L/TLDYPARAH 0.4
ORF1/GT3 B9 T735I LPHPTPPVS 0.5 LPHPT/IPPVS 0.6
  B10 G1632R ERAEQLRLA 0.1 ERAEQLG/RLA 0.1
ORF2/GT3 B11 L477T SLTAAEYDQ 1.1 SLL/TAAEYDQ 0.5
  B12 L613T LIDYPARAH 0.5 L/TIDYPARAH 0.4
ORF1/GT4 B13 V735I TPVAVDVPP 0.5 TPVAV/IDVPP 0.6
  B14 Y1587F CGLKLKVDY 0.7 CGLKLKVDY/F 1.7
  B15 G1634R KNWGPGSEG 1.8 KNWGPGSEG/R 1.7