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. 2018 Mar 19;9(1):683–699. doi: 10.1080/21505594.2018.1438025

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© 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Nuclear hormone receptors are required for defense against Enterococcus. (a) Effect of E. faecalis and E. faecium infection on the survival of wild-type N2 and nhr-114(gk849). (b) Effect of E. faecalis and E. faecium infection on fer-15(b26);fem-1(hc17) C. elegans treated with L4440 vector control or nhr-144 RNAi. Results are representative of 2 independent assays. Each graph shows the average of three plates for each strain, with each plate containing 30–40 worms. Relevant statistically significant survival curves (relative to control) are marked with asterisks and a bracket. Statistical significance of differences between survival curves was calculated using Kaplan-Meier log rank analysis.