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. 2018 Apr 18;9(1):724–737. doi: 10.1080/21505594.2018.1441589

Figure 1.

Figure 1.

Phylogenetic tree analysis and sequence homology of TFPI-1. (a) From a total of 87 vertebrate species, a phylogenetic tree for the TFPI-1 C-terminal was constructed using Neighbour-Joining tree with 1000 bootstrap replications using the Mega 6 software. (b) Human plasmin and thrombin enzymatic cleavage sites on human TFPI-1 are indicated with arrows. ClustalW multiple sequence alignment of the TFPI-1 C-terminal highlighting amino acids with at least 70% similarity in all species.