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. 2018 May 16;13(5):e0195932. doi: 10.1371/journal.pone.0195932

Table 2. Top 25 pathways among 1116 identified to be activated in the Bcx087 IBC model.

Pathway Number Total pValue
Gene expression 1066 1631 3.10E-121
Cell Cycle 422 566 3.40E-72
Cell Cycle, Mitotic 356 462 2.50E-67
Infectious disease 274 348 2.26E-55
M Phase 219 268 1.66E-49
Processing of capped intron-containing pre mRNA 167 193 9.64E-45
Metabolism of Proteins 620 1074 1.16E-41
mRNA processing (MMU) 282 398 3.17E-41
Translation 135 151 6.03E-40
Influenza life cycle 123 136 9.86E-38
Influenza Infection 130 147 2.49E-37
Influenza viral RNA Transcription and Replication 115 128 1.09E-34
mRNA Splicing–Major Pathway 119 134 1.10E-34
HIV Infection 173 222 2.63E-34
mRNA Splicing 125 144 4.25E-34
Cap-dependent Translation initiation 104 114 6.70E-33
Eukaryotic Translation initiation 104 114 6.70E-33
Cellular response to stress 251 367 8.55E-33
Mitotic Metaphase and Anaphase 141 174 1.55E-33
GTP hydrolysis and joining of the 98 107 1.99E-31
SRP-dependent co-translational protein targeting to membrane 98 107 1.99E-31
Mitotic Anaphase 140 173 3.36E-31
rRNA processing 144 180 5.05E-31
L13a-mediated translational silencing of Ceruloplasmin expression 96 106 7.84E-30
3’-UTR-mediated translational regulation 96 106 7.84E-30