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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Pharm Sci. 2017 Apr 27;106(9):2566–2575. doi: 10.1016/j.xphs.2017.04.040

Table 1.

Transport properties by MRP4

MRP4-expressing vesicle uptake
Reference
MRP4-ATP MRP4-AMP ATP/AMP ratio
μL/5min/mg
cefazolina 76.7 0.2 471 18)
cefmetazolea 103 3 31 18)
methotrexate 30.2 1.6 19
raltitrexed 61.0 3.4 18
[3H]pravastatin 18.4 1.7 11
[3H]DHEAS 1443 143 10
[3H]pitavastatin 162 43 3.8
furosemidea 118 41 2.9 19)
hydrochlorothiazidea 2.87 1.53 1.9 19)
a

the transport activities were cited from the reference indicated for comparison.