Table 2. The effect of thiamine and TPP on histopathological damage induced with cisplatin.
| Variables | Groups | |||||
|---|---|---|---|---|---|---|
| CIS | CTM | CTPP | HG | TM | TPP | |
| Edema | 3 (3–3)* | 3 (2–3) | 1 (1–2)** | 0 (0–0) | 0 (0–0)** | 0 (0–0)** |
| Vascular congestion | 3 (2–3)* | 3 (2–3) | 0 (0–0)** | 0 (0–0) | 0 (0–0)** | 0 (0–0)** |
| Fascicular destruction | 3 (2–3)* | 2,5 (1–3) | 0 (0–0)** | 0 (0–0) | 0 (0–0)** | 0 (0–0)** |
Data are presented as the median (min-max). The P-values represent Mann-Whitney U test results. *P<0.001, compared with HG group. **P<0.001, compared with CIS group.