Figure 4.

Exo^H promotes angiogenesis and reduces cardiac apoptosis after infarction. (A) Capillary at the border zone on day 28 after MI was identified by staining with CD31 (red) and nuclei (blue). (B) Quantification of CD31⁺ cells in A (n = 8). (C) Arterioles at the border zone on day 28 after MI were identified by staining with α-SMA (green) and nuclei (blue). (D) Quantification of α-SMA⁺ cells in C (n = 8). (E) Quantification of TUNEL⁺ cells in Supplemental Figure S3(A). Apoptosis rate was quantified as the percentage of cells that were positive for TUNEL staining. (F) Quantification of Sca-1⁺ cells in Supplemental Figure S3(B) (n = 6). *p < .05, vs. PBS; #p < .05, vs. Exo^N. Scale bar =100 μm.