. Author manuscript; available in PMC: 2018 Jul 1.

Published in final edited form as: J Intensive Care Med. 2017 Jan 1:885066617741284. doi: 10.1177/0885066617741284

Table 3.

Features of Sepsis Encounters for all Patients, Derivation Set, and Validation Set.^a

Variable	Overall, n = 3297	Derivation Set, n = 2209	Validation Set, n = 1088	P Value
Initial vital signs
SBP (mm Hg)	123.6 (30.5); n = 3013	123.8 (30.9); n = 2010	124.1 (30.2); n = 982	.471^b
HR (beats/min)	103.4 (22.9); n = 3168	103.4 (23.0); n = 2124	103.5 (22.9); n = 1044	.884^b
RR (breaths/min)	19.8 (5.1); n = 3292	19.8 (5.1); n = 2206	19.8 (5.2); n = 1086	.954^b
Temperature (°F)	99.1 (2.3); n = 3294	99.0 (2.3); n = 2208	99.2 (2.3); n = 1086	.092^b
SpO₂ (%)	96.2 (5.4); n = 1135	96.2 (5.3); n = 2204	96.1 (5.5); n =1 083	.186^b
Laboratory findings
Initial WBC (thousand/mm³)	14.5 (7.8); n = 3296	14.4 (7.7); n = 2208	14.5 (8.1); n = 1088	.973^b
Lactate, (mmol/L)	2.8 (2.9); n = 1647	2.9 (2.9); n = 1099	2.8 (2.9); n = 548	.640^b
Lactate, n (%)
≥ 4 mmol/L	274 (17)	184 (17)	90 (16)	.982^c
2 to 3.9 mmol/L	530 (32)	354 (32)	176 (32)
< 2 mmol/L	843 (5)	561 (51)	282 (52)
Creatinine (mg/dL)	1.8 (2.1); n = 3297	1.8 (2.0); n = 2209	1.9 (2.3); n = 1088	.953^b
Positive culture, n (%)
Blood	969 (36)	642 (36)	327 (35)	.668^c
Respiratory	666 (25)	443 (25)	223 (24)
Urine	911 (34)	597 (33)	314 (34)
Wound	164 (7)	101 (6)	63 (7)
Outcomes
Inpatient mortality	332 (10.1)	220 (10)	112 (10)	.764^c
ICU LOS ≥3 days	748 (22.7)	487 (22)	261 (24)	.210^c
Severity of Illness, n (%)
qSOFA Positive (≥2)	537 (16)	371 (17)	166 (15)	.505^c
qSOFA negative (<2) and SOFA≥2	1287 (39)	861 (39)	426 (39)
qSOFA negative (<2) and SOFA <2	1473 (44)	977 (44)	496 (46)

Abbreviations: HR, heart rate; ICU, intensive care unit; qSOFA, quick sequential organ failure assessment; RR, respiratory rate; SBP, systolic blood pressure; WBC, white blood cell count; LOS, length of stay.

Data are means (SDs), unless otherwise specified.

Wilcoxon rank sum test.

Pearson χ² test.