Table 4.
Sensitivity and Specificity for Inpatient Mortality for all Sepsis Encounters and qSOFA-Negative Encounters.a,b,c
| Sensitivity and Specificity for Inpatient Mortality for All Sepsis Encounters (n = 3297) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Variable | Inpatient Mortality, N (%)
|
Sensitivity (95% CI)
|
Specificity (95% CI)
|
||||||
| Total | Derivation | Validation | Total | Derivation | Validation | Total | Derivation | Validation | |
| SOFA ≥ 2 | 299 (17) | 198 (16) | 101 (17) | 90%(87% to 93%) | 90%(86% to 94%) | 90%(85% to 96%) | 50%(48% to 52%) | 50%(47% to 52%) | 51%(48% to 54%) |
| qSOFA≥ 2 | 125 (23) | 87 (23) | 38 (23) | 38%(32% to 43%) | 40%(33% to 46%) | 34%(25% to 43%) | 86%(85% to 87%) | 86%(84% to 87%) | 87%(85% to 89%) |
| Simple SOFA ≥ 2 | 298 (15) | 194 (15) | 104 (16) | 90%(86% to 93%) | 88%(84% to 92%) | 93%(88% to 98%) | 44%(42% to 46%) | 44%(42% to 47%) | 44%(40% to 47%) |
|
| |||||||||
| Sensitivity and Specificity for Inpatient Mortality for qSOFA-Negative Encounter (n=2760) | |||||||||
|
| |||||||||
| SOFA score ≥ 2 | 177 (14) | 114 (13) | 63 (15) | 86%(81% to 90%) | 86%(80% to 92%) | 85%(77% to 93%) | 57%(55% to 58%) | 56%(54% to 59%) | 57%(54% to 61%) |
| Simple SOFA ≥ 2 | 182 (12) | 115 (12) | 67 (13) | 88%(83% to 92%) | 86%(81% to 92%) | 91%(84% to 97%) | 48%(47% to 50%) | 48%(46% to 51%) | 48%(45% to 51%) |
Abbreviations: CI, confidence interval; qSOFA, quick sequential organ failure assessment; SOFA, sequential organ failure assessment.
a
n = 3297.
b
Inpatient mortality by SOFA, qSOFA, and simple SOFA ≥ 2 for all septic encounters and encounters with qSOFA negative for derivation and validation sets.
c
Percentage is inpatient mortality divided by total number of patients with each score ≥2.