Table 2.
Risk of all-cause, CVD, and cancer mortality by physical activity levels (N = 6,382).
| Physical Activity Tertile | P-Trend | |||
|---|---|---|---|---|
| 1 (low) | 2 | 3 (high) | ||
|
|
||||
| All-cause deaths | ||||
| Total PA, deaths (ratea) | 259 (38.2) | 124 (17.8) | 67 (9.4) | |
| RR (95% CI)b | 1.00 (ref) | 0.58 (0.47, 0.73) | 0.38 (0.28, 0.51) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.68 (0.54, 0.85) | 0.49 (0.37, 0.66) | <.001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.73 (0.57, 0.93) | 0.56 (0.41, 0.76) | <.001 |
|
| ||||
| Low light PA, deaths (ratea) | 211 (30.8) | 135 (19.3) | 104 (14.8) | |
| RR (95% CI)b | 1.00 (ref) | 0.77 (0.61, 0.95) | 0.69 (0.54, 0.89) | .002 |
| RR (95% CI)c | 1.00 (ref) | 0.86 (0.69, 1.08) | 0.80 (0.62, 1.03) | .074 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.91 (0.71, 1.15) | 0.87 (0.66, 1.14) | .28 |
|
| ||||
| High light PA, deaths (ratea) | 263 (38.7) | 113 (16.2) | 74 (10.4) | |
| RR (95% CI)b | 1.00 (ref) | 0.49 (0.39, 0.62) | 0.36 (0.28, 0.48) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.57 (0.45, 0.71) | 0.47 (0.35, 0.61) | <.001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.61 (0.47, 0.78) | 0.57 (0.42, 0.76) | <.001 |
|
| ||||
| MVPA, deaths (ratea) | 280 (41.9) | 116 (16.6) | 54 (7.6) | |
| RR (95% CI)b | 1.00 (ref) | 0.54 (0.43, 0.67) | 0.31 (0.23, 0.42) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.63 (0.50, 0.79) | 0.42 (0.30, 0.57) | <.001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.66 (0.51, 0.84) | 0.46 (0.33, 0.65) | <.001 |
|
| ||||
| CVD deaths | ||||
| Total PA, deaths (ratea) | 97 (14.3) | 43 (6.2) | 14 (1.9) | |
| RR (95% CI)b | 1.00 (ref) | 0.56 (0.39, 0.81) | 0.23 (0.13, 0.41) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.64 (0.44, 0.94) | 0.29 (0.16, 0.53) | <.001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.66 (0.44, 1.01) | 0.34 (0.18, 0.64) | <.001 |
|
| ||||
| Low light PA, deaths (ratea) | 82 (11.9) | 41 (5.9) | 31 (4.4) | |
| RR (95% CI)b | 1.00 (ref) | 0.61 (0.42, 0.89) | 0.55 (0.35, 0.85) | .003 |
| RR (95% CI)c | 1.00 (ref) | 0.69 (0.47, 1.02) | 0.64 (0.41, 0.99) | .029 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.78 (0.51, 1.18) | 0.72 (0.44, 1.18) | .16 |
|
| ||||
| High light PA, deaths (ratea) | 100 (14.7) | 37 (5.3) | 17 (2.4) | |
| RR (95% CI)b | 1.00 (ref) | 0.44 (0.30, 0.65) | 0.24 (0.14, 0.39) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.50 (0.34, 0.74) | 0.30 (0.17, 0.51) | <.001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.49 (0.32, 0.76) | 0.33 (0.18, 0.59) | <.001 |
|
| ||||
| MVPA, deaths (ratea) | 99 (14.8) | 39 (5.6) | 16 (2.2) | |
| RR (95% CI)b | 1.00 (ref) | 0.57 (0.39, 0.53) | 0.31 (0.18, 0.53) | <.001 |
| RR (95% CI)c | 1.00 (ref) | 0.68 (0.45, 0.99) | 0.42 (0.24, 0.75) | .001 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.68 (0.44, 1.05) | 0.43 (0.23, 0.81) | .005 |
|
| ||||
| Total cancer deaths | ||||
| Total PA, deaths (ratea) | 42 (6.2) | 23 (3.3) | 22 (3.1) | .135 |
| RR (95% CI)b | 1.00 (ref) | 0.62 (0.37, 1.05) | 0.68 (0.39, 1.19) | .476 |
| RR (95% CI)c | 1.00 (ref) | 0.71 (0.42, 1.19) | 0.85 (0.47, 1.51) | .34 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.68 (0.38, 1.20) | 0.76 (0.41, 1.43) | |
|
| ||||
| Low light PA, deaths (ratea) | 34 (4.9) | 32 (4.6) | 21 (2.9) | |
| RR (95% CI)b | 1.00 (ref) | 1.05 (0.64, 1.72) | 0.76 (0.43, 1.35) | .382 |
| RR (95% CI)c | 1.00 (ref) | 1.13 (0.69, 1.87) | 0.82 (0.46, 1.48) | .571 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.98 (0.57, 1.69) | 0.79 (0.42, 1.46) | .47 |
|
| ||||
| High light PA, deaths (ratea) | 38 (5.6) | 27 (3.9) | 22 (3.1) | |
| RR (95% CI)b | 1.00 (ref) | 0.79 (0.48, 1.29) | 0.69 (0.39, 1.21) | .182 |
| RR (95% CI)c | 1.00 (ref) | 0.90 (0.54, 1.49) | 0.87 (0.49, 1.54) | .613 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.76 (0.43, 1.34) | 0.87 (0.47, 1.59) | .59 |
|
| ||||
| MVPA, deaths (ratea) | 43 (6.4) | 30 (4.3) | 14 (1.9) | |
| RR (95% CI)b | 1.00 (ref) | 0.83 (0.51, 1.34) | 0.45 (0.23, 0.85) | .017 |
| RR (95% CI)c | 1.00 (ref) | 0.95 (0.58, 1.56) | 0.59 (0.30, 1.15) | .155 |
| RR (95% CI)d (N=5479) | 1.00 (ref) | 0.92 (0.54, 1.58) | 0.59 (0.29, 1.21) | .18 |
a
Crude death rate per 1,000 person years.
b
Adjusted for awake accelerometer wear-time (hr/d) and age (years).
c
Adjusted for awake accelerometer wear-time (hr/d), age (years), race-ethnicity (white, black, Hispanic), education (high school or less, some college, college or more), current smoking (no, yes), alcohol intake past 3 months (none, <1, ≥1 drinks/week), age at menopause (years), self-rated general health (excellent, very good, good, fair, poor), and number of comorbid conditions (0–10, continuous).
d
Adjusted for above covariables plus SPPB score (0–12, continuous); N=5479 (384 total deaths, 128 CVD deaths, 75 cancer deaths).