Table 1.
tracers | LoganREF
|
RTM
|
||||
---|---|---|---|---|---|---|
BPND | R1 | k2 (min−1) | k3 (min−1) | k4 (min−1) | BPND(k3/k4) | |
18F-TZ19106Ba | 4.36 ± 0.91 | 0.85 ± 0.16 | 0.059 ± 0.008 | 0.052 ± 0.008 | 0.011 ± 0.002 | 4.70 ± 0.64 |
18F-TZ8110b | 2.02 ± 0.70 | 0.89 ± 0.05 | 0.058 ± 0.004 | 0.041 ± 0.009 | 0.020 ± 0.003 | 2.15 ± 0.66 |
n = 5 in 3 NHPs.
n = 6 in 3 NHPs.