Table 1.
Pt No | Source | % Blasts | Disease status | FLT3 status | Cytogenetic | experiments |
---|---|---|---|---|---|---|
1 | PB | 90 | New diagnosis | WT | 46,XY | C-82 |
2 | PB | 70 | New diagnosis | ITD | 46,XY | C-82 |
3 | PB | 93 | Relapse/refractory | WT | Complex karyotype | C-82 |
4 | PB | 74 | Relapse/refractory | WT | Complex karyotype | C-82 |
5 | PB | 84 | Relapse/refractory | WT | Complex karyotype | C-82 |
6 | BM | 74 | Relapse/refractory | WT | Complex karyotype | C-82 |
7 | PB | 78 | Relapse/refractory | WT | Complex karyotype | C-82 |
14 | BM | 52 | Primary refractory | ITD + D835 | 47,XY, +9 | C-82 + TKI |
15 | BM | 74 | New diagnosis | D835 | 47,XY,inv(16),+22,del(7) | C-82 + TKI |
16 | PB | 56 | Relapse/refractory | ITD | 46,XY | C-82 + TKI |
17 | BM | 83 | Relapse | D835 | 46,XY | C-82 + TKI |
18 | PB | 52 | New diagnosis | D835 | 46,XY | C-82 + TKI |
19 | PB | 72 | Relapse/refractory | D835 | 46,XY | C-82 + TKI |
20 | BM | 61 | Relapse | WT | 46,XX | C-82 + TKI |
21 | BM | 60 | New diagnosis | WT | 46,XX | C-82 + TKI |
22 | BM | 97 | Relapse | WT | 46,XY, t(1;3), del(7) | C-82 + TKI |
23 | BM | 78 | Relapse/refractory | ITD | 46,XY | Mouse experiments |
Pt No, patient number.