Table 1.
Histopathology of wt-CRPV papillomas for individual animals
A | Animal Number | Increased Cell Infiltrate | Acanthosis | Koilocytes | Stratum Corneum Thickening | Parakeratosis |
---|---|---|---|---|---|---|
3422 | X | X | X | X | X | |
3423 | X | X | X | X | X | |
3424 | X | X | X | X | X | |
3425 | X | X | X | X | X | |
B | Animal Number | Increased Cell Infiltrate | Acanthosis | Koilocytes | Stratum Corneum Thickening | Parakeratosis |
| ||||||
3412 | X | |||||
3413 | X | X | X | X | ||
3414 | X | X | X | X | X | |
3415 | X | |||||
3416 | X | X | X | X | X |
Presence of histopathology features in wt-CRPV papillomas from animals treated with A. vehicle (group D) and B. 1.5% w/v I-BET762 (group C). Examples of pathology are illustrated in S5.