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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Neurobiol Aging. 2018 Mar 21;67:108–119. doi: 10.1016/j.neurobiolaging.2018.03.015

Figure 4. Short-term depression is profoundly increased in older mice.

Figure 4

A. Example traces of responses to 100 Hz stimulation, illustrating greater short-term depression in synapses from older mice (18-month, red traces). B. Summary plot of EPSC amplitude during the stimulus train, normalized to the amplitude of the first response. C. Summary plot of decay constant derived from monoexponential fit of depression curves per cell, as shown in B. D. Summary plot of steady-state evoked amplitudes obtained per cell from trains between 300–500 ms.