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. 2018 Mar 2;37(20):2702–2713. doi: 10.1038/s41388-018-0137-z

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, and provide a link to the Creative Commons license. You do not have permission under this license to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6 — USP27 and Cyclin E expression are upregulated in hepatocellular carcinoma cells and tissues. a Western blot analysis of Cyclin E, USP27, and Fbxw7 expression in various kinds of cancer cell lines. GAPDH was used as loading control. b Cyclin E, USP27, and Fbxw7 expression in various kinds of hepatocellular carcinoma cell lines were analyzed. c, d The expression of USP27, Cyclin E, and Fbxw7 were measured in HCC and normal tissue c and quantified d. e Representative images of immunohistochemical staining of USP27, Cyclin E, and Fbxw7. Scale bars, 100 μm