Table 2.

Comparison of particulate matter in all infusion combinations including the addition of IV in-line filtration.

Infusion set combination*	Particulate contamination analysis	Mean difference	95% confidence interval of difference	Adjusted p-value
Combination 2 “with filter and CVC” vs. combination 4 “with filter only”	Overall particulate matter	6,887	−6,761 to 20,536	0.4343
	Particulate matter size ≥10 µm	29	−1,240 to 1,298	0.9982
	Particulate matter size ≥25 µm	2	−11 to 14	0.9495
Combination 3 “with filter + extension line” vs. combination 4 “with filter only”	Overall particulate matter	43,442	29,793 to 57,090	<0.0001
	Particulate matter size ≥10 µm	−3,513	−4,782 to −2,244	<0.0001
	Particulate matter size ≥25 µm	22	10 to 34	0.0004
Combination 2 “with filter and CVC” vs. combination 3 “with filter and extension line”	Overall particulate matter	−36,554	−50,203 to −22,906	<0.0001
	Particulate matter size ≥10 µm	3,513	2,244 to 4,782	<0.0001
	Particulate matter size ≥25 µm	−20	−33 to −8	0.0008

^*Infusion set combinations are represented by the volume V, corresponding to the internal volume of the IV tubing between the in-line filter and the Qicpic particle counter, i.e. V = 0.8 mL, 1.7 mL and 0 mL for combinations 2, 3 and 4, respectively.