Table 2.
Summary of the most important metabolites detected with 1H-NMR and GC-MS resulting from the analysis between HC and SSc and between dcSSc and lcSSc.
| Metabolites Model HC vs SSc | HC | SSc | Metabolites Model dcSSc vs lcSSc | dcSSc | lcSSc | |
|---|---|---|---|---|---|---|
| 1H-NMR | Acetate | + | − | Acetate | + | − |
| Glutamate | + | − | Fructose | + | − | |
| Dimethylurate | + | − | Glutamate | + | − | |
| Lysine | + | − | Glycerol | + | − | |
| 3-OH-butyrate | − | + | Lysine | + | − | |
| Lactate | − | + | Valine | + | − | |
| Lactate | − | + | ||||
| Glutamine | − | + | ||||
| GC-MS 1H-NMR | Alanine | + | − | Sugars | − | + |
| Aspartic acid | + | − | ||||
| Citric Acid | + | − | ||||
| Sugars | − | + | ||||
| GC-MS | 2-pyrrolidone | − | + | Sorbitol | − | + |
| D-threitol | − | + | Glycerate | + | − | |
| Butanoic Acid | − | + | Glutarate | + | − | |
| Glutaric Acid | + | − | ||||
| L-threonic Acid | + | − | ||||
| 1–5-anhydrosorbitol | + | − |