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. 2018 May 16;9:1929. doi: 10.1038/s41467-018-04332-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Description of samples, technology and methods used for the analysis of the two stages of our study. Abbreviations: NMO, neuromyelitis optica; NMO-IgG+, neuromyelitis optica positive for autoantibodies for AQP4; NMO-IgG−, neuromyelitis optica negative for autoantibodies for AQP4; MAF, minor allele frequency; SNP, single-nucleotide polymorphism. NMO cases were obtained from the Accelerated Cure Project. Stage I controls included neurological normal individuals from the Genomic Psychiatry Cohort. Stage II controls were neurological normal individuals from Coriell collections (Methods)