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. 2018 May 16;8:7689. doi: 10.1038/s41598-018-25990-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) The results of western blotting have been shown using antibodies Bax, Bcl–2 and p-53 in treatment and control group. The images of control, direct plasma and indirect plasma + drug groups were plotted on a same gel and the images of drug and indirect plasma groups were plotted on another gel. (B) Relative protein levels in 5 different groups. (P-values < 0.05 (*), P-values < 0.01 (**) and P-values < 0.001 (***)).